NeuroImaging Software package

The NIS (NeuroImaging Software) package is a collection of UNIX-based programs and shell scripts used for conducting each of the primary steps involved in preprocessing and analyzing neuroimaging datasets, including mean normalization and statistical analysis using ANOVA and post-hoc contrasts on both single subjects and across groups of subjects. Some simple visualization and data reporting tools are also included. Most of the programs are provided with an optional graphical user interface (written in Java). The NIS package uses the ANALYZE format (16-bit integer) for all image data.

Distribution Information

Current release: nis-3.5 August 1, 2001
Download: The release files are available via anonymous ftp from kraepelin.wpic.pitt.edu (136.142.95.29) in /nis, or you may download the release file here: nis35.tar.gz.crypt (479 KB). Test datasets (with sample output) are available separately: demo_be.tar.gz (10MB, big-endian, for Sun/SGI machines), and demo_le.tar.gz (10MB, little-endian, for Intel machines).
Please contact Kate Fissell, fissell+@pitt.edu, if you have questions.
Cost: NIS software is distributed free of charge.
Installation: The NIS package is distributed as an encrypted gzipped tar file. After you have downloaded the file, email Kate Fissell(fissell+@pitt.edu) to receive the password for decrypting, and then run the following commands: 
   crypt < nis35.tar.gz.crypt > nis35.tar.gz
   gunzip nis35.tar.gz
   tar xf nis35.tar
Note: Linux users without crypt may get an equivalent program, enigma, from the brl-cad site
After unpacking the package, be sure to read the README file for installation.
Copyright: Unless otherwise noted in the source code, the copyright for all NIS software is held by the Laboratory for Clinical Cognitive Neuroscience, University of Pittsburgh, and the Neuroscience of Cognitive Control Laboratory, Princeton University.
Disclaimer: The software is provided "as-is" and without warranty of any kind, express, implied or otherwise, including without limitation, any warranty of merchantability or fitness for a particular purpose. In no event shall the copyright holders be liable for any special, incidental, indirect or consequential damages of any kind, or any damages whatsoever resulting from loss of use, data or profits, whether or not advised of the possibility of damage, and on any theory of liability, arising out of or in connection with the use or performance of this software.

Credits

NIS code was developed by the Clinical Cognitive Neuroscience (CCN) and Neuroscience of Cognitive Control (NCC) laboratories. Original coding was done by Jonathan D. Cohen, Todd Braver, Robert Orr, Leigh Nystrom, and Steven Forman. Further development by Kate Fissell, Victor Ortega, and Sylvain Takerkart. Significant contributions to the package were made by Fred Sabb and Deanna Barch by virtue of their intensive testing and use of the software.

Test data

A test dataset, courtesy of Andy Stenger, University of Pittsburgh Medical Center Magnetic Resonance Research Center, is provided alongside the NIS distribution. It is a 48-timepoint finger-tapping on/off paradigm. For more information, see the README file in the demo directory.

Related Links

The following links refer to programs or packages directly used by the NIS programs or scripts. Please refer back to the CCN or NCC homepage for a more general listing of software packages used by our labs.

Last updated October 20, 2000
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